In chemistry hydrophosphonylation refers to any reaction where addition across a double bond generates a phosphonate (RP(O)(OR')2) group. Examples include the Kabachnik–Fields reaction, where a dialkylphosphite reacts across an imine to form an aminophosphonate. The reaction is catalyzed by bases and is subject to organocatalysis. Important compounds generated by this reaction include the common herbicide glyphosate.

Hydrophosphonylation reactions

  • Kabachnik–Fields reaction
  • Pudovik reaction
  • Abramov reaction

See also

  • Hydrophosphination - the addition of a phosphine derivative (PHR2) across a double bond

References


Phosphonate synthesis by substitution or phosphonylation

Phosphonate synthesis by substitution or phosphonylation

Katalytische Hydrierung acetylenischer Phosphoniumsalze Patent 0100839

Catalyst and solventfree hydrophosphination and

Hi Phos Markenblattdünger FMC Agricultural Solutions Deutschland